重视脂肪胰的基础和临床研究 [中文引用][英文引用]

 【摘要】 脂肪胰作为一种肥胖相关代谢综合征(MS)组份并不罕见，不仅与MS相关疾病关系密切，而且在胰腺炎、胰腺癌和胰瘘风险中起重要作用。相较于肝脏组织，胰腺对脂肪沉积更敏感，脂肪胰发生早于代谢相关脂肪性肝病。但目前对脂肪胰重视度和知晓度不容乐观。本文概述了脂肪胰的发病机制、病理生理学、与其他临床疾病的关系、诊断预防和治疗现状，阐述了目前对其了解的局限性和争议性，以引起对其基础和临床研究的重视。

【Abstract】  Fatty pancreas (FP) is not uncommon as a component of obesity-related metabolic syndrome. It is not only closely related to metabolic syndrome-related diseases, but also plays a causative role in the risk of pancreatitis, pancreatic cancer and pancreatic fistula. Compared with metabolic dysfunction-associated fatty liver disease (MAFLD), current status is not optimistic about the degree of attention and awareness of FP that even occurs earlier than MAFLD. This editorial outlines several important issues of FP in pathogenesis, pathophysiology, correlation with other clinical diseases, diagnosis, prevention and treatment status, and summarizes the limitations and controversies of the current understanding in FP, in order to attract attention to its basic and clinical research.